李欢欢，李莎莎，海力茜·陶尔大洪^*

（新疆医科大学药学院，新疆乌鲁木齐 830000）

摘要：响应面法优选新疆红芪多糖提取工艺。以新疆红芪多糖提取率为参考指标，在提取温度、时间、料液比进行单因素实验的基础上，利用响应面法优选提取条件。最佳优化提取工艺为提取温度88.77 ℃，提取时间2.83 h，料液比1∶30.24（g/mL），在该优化条件下，新疆红芪精制多糖的实际提取率为3.56%。利用响应面法优化新疆红芪多糖提取工艺是合理可行的。

关键词：新疆红芪；多糖；响应面法；提取工艺

中图分类号：R284.2   文献标识码：A   文章编号：1674-506X（2020）02-0045-0006

The Response Surface Method Optimization Xinjiang Red Stilbene Polysaccharide Extraction Process

LI Huan-huan, LI Sha-sha, HAI Li-qian^*

（School of Pharmacy, Xinjiang Medical University, Urumqi Xinjiang 830000, China）

Abstract：The response surface method was optimized for the extraction of polysaccharides from Xinjiang red peony. The extraction rate of polysaccharides from Xinjiang red peony was used as a reference index. Based on the single factor experiment of extraction temperature, time and solid-liquid ratio, the response surface method was used to optimize the extraction conditions. The optimum extraction process was as follows: extraction temperature was 88.77 ℃, extraction time was 2.83 h, and the ratio of material to liquid was 1∶30.24 (g/mL). Under the optimized conditions, the actual extraction rate of Xinjiang red peony polysaccharide was 3.56%. It is reasonable and feasible to optimize the extraction process of Xinjiang red peony polysaccharide by response surface methodology.

Keywords：Xinjiang red peony; polysaccharide; response surface method; extraction process

doi：10.3969/j.issn.1674-506X.2020.02-008

收稿日期：2019-07-19

基金项目：新疆维吾尔自治区少数民族科技骨干特培专项基金（2003-4）；大学生创新创业训练计划项目（CX2016040）；自治区“十三五”重点学科建设经费（1007）

作者简介：李欢欢（1995-），女，硕士。研究方向：天然药物研究与开发。

*通讯作者

引文格式：李欢欢,李莎莎,海力茜·陶尔大洪.响应面法优选新疆红芪多糖提取工艺[J].食品与发酵科技,2020,56(2):45-49,63.